I think J Jonah Jameson is going to clone himself in an effort to take Spiderman out of the picture, but due to a radioactive leak in his Clone-O-Meter, the clone becomes none other than Ultimate Spidercide. Meanwhile, on the other side of town, mild mannered Proffessor Miles is bitten by a radioactive jackal, and transforms into......... The Lesser Spotted Hyena! A mindless, slavering Spidercide tracks down a confused Nick Fury, believing him to be his father, and then joins with him to create Ultimate Toxin. The Lesser Spotted Hyena runs into Toxin, and the two fight to the death over Nick Fury's supple body, when the battle is interrupted by none other than Spiderman. Amid the vicious battle, Toxin and the Lesser Spotted Hyena implode into eachother, creating the Beyonder, and he flies off to play chess with Gah Lak Tus. However, Nick Fury is left brutally injured after a passing pigeon flies into his head, and in his dying breaths, reveals his undying love for Peter. Peter cradles the dying Fury, and in his last moments, Fury hands Peter his eyepatch.
Epilogue: Nick Fury's funeral. Captain American is bawling like a baby, and Peter reads a eulogy, dressed in his black costume. Meanwhile, across town, a suspicious looking pigeon perches in his coop on a rooftop. He emits a low chuckle, and rips off his pigeon mask, to reveal none other than....... Ultimate Chameleon!