most of these suggestions are stories not events
If handled well, Civil War would be pretty good
Annihilation, I would die for
Messiah CompleX would work really well if they could somehow do it without all the back story
You guys should stop just mentioning "epic" comic book stories or stories you really like and, before you post them, think about whether or not the general movie ticket-buying public would indeed buy tickets to see them. Annihilation and Kree/Skull War, Batman: Knightfall - no way.
They did The Death of Superman (animated) and it was a steaming pile of ****. Following the original storyline more closely would probably be worse.
I think the Kree/Skrull war would be an excellent third Avengers film.
I still say Kingdom Come would make a great film even if it's just animated.
You guys REALLY think those would be "great films" or you would just like to see them made into films?
I didn't think either were particularly great comics to begin with, so maybe it's just me.